• 专利附录
  • 专利说明
  • 权利要求
  • 类似技术
  • 同族专利
  • 引用文献
  • 法律状态
  • 优先权
    • 专利摘要:
    A method of manufacturing tablets in a press having a rotary die plate cooperating with a filling device including a rotary filling wheel and a rotary dosing wheel arranged on top of the die plate, and a plurality of die plungers each projecting into an assigned die in the plate, and further including means for adjusting the vertical position of the plunger; the method comprising the steps of adjusting the rotational speeds of the filling and dosing wheels to a value at which minimum variations of compressing forces take place, comparing a predetermined range of variations of the compressing forces with the measured actual values and adjusting the weight of the tablets in process by readjusting the vertical position of the plunger in response to the ascertained difference, and thereafter readjusting the rotational speeds of the wheels to minimize the variations of the readjusted compressing forces.
    公开号:SU862816A3
    申请号:SU782664448
    申请日:1978-09-21
    公开日:1981-09-07
    发明作者:Штюбен Вернер；Хинцпетер Юрген；Дойш Рудольф；Фридрихс Конрад
    申请人:Вильхельм Фетте Гмбх (Фирма)；
    IPC主号:
    专利说明:

    - .Г

    The invention relates to the treatment of materials by pressure and can be used in chemical, pharmaceutical and other industries in the manufacture of tablets from powder materials.
    A known method of manufacturing tablets from powder materials consists in loading a metered amount of powder with a paddle feeder. We feed into the cavity of the matrix and press the oppositely displaced upper and lower punches to control the volume of the cavity of the matrix and change the position of the loaded powder by changing the number of revolutions. vane feeder {.
    The disadvantage of this method. is the poor quality of the tablets, per hour 1 and significant deviations of the density 4 and the mass of the tablets, due to the lack of control of the pressing force,. This strength is determined by the number of cells and the time of their dissolution or decomposition.
    The purpose of the invention is to improve the quality of the tablets by providing them with a given density and mass.
    5 This is achieved by the method of making tablets from powder materials, which consists in loading the metered amount of powder with a paddle feeder into the cavity.
    10 of the die and subsequent pressing by the moving upper and lower punches with volume control of the die cavity by changing the position of the lower punch relative to the die and adjusting the amount of powder loaded by changing the number of revolutions of the blade feeder, while adjusting the amount of powder loaded by measuring
    The 20 forces of each pressing determine the range of variation of the pressing force and regulate the amount of powder to be loaded until the range of force change of each
    ; 25 later extrusion in comparison with the previous one will not reach the minimum value, and when adjusting the volume of the die cavity, the deviations are recorded
    30, the forces of each pressing from the reference value and adjust the volume of the die cavity until the deviation of the pressing force from the reference value reaches the minimum value.
    Regulation of the amount of powder loaded and the volume of the cavity of the matrix can be carried out sequentially.
    The figure shows the principal press of the press, which allows the proposed method to be made to manufacture tablets from powder materials.
    The press consists of a rotating disk 1 with dies 2, into which the lower punches 3 come in from the bottom. 6. Dosing zone b lies slightly above the loading zone 5.
    In the loading area 5 above the matrix disk 1, the loading wheel 7 of the blade feeder is installed, in the dosing area 6 above the matrix disk 1 - the dosing wheel 8. The number of revolutions of the loading wheel 7 and thereby the dosing wheel B is adjusted by the electric motor 9.
    The servo motor 10 can set the height of the loading 5 and dosing 6 zones, for example, in the adjustment range of about 3 mm in the direction of the double arrow, and the number of revolutions of the filling and dosing wheels in the range from 5 to 100 rpm. Production of tablets of the same weight, which corresponds to a given weight, and using the same pressing force is produced by determining the value of the measured forces, which depend on the weight of the compressed tablets.
    When the press is working on the manufacture of tablets, each punch post during each pressing process gives a signal to be assessed about the pressing force through strain gauge transducers or strain gages, which are located in the bridge circuit of the measuring unit 11. These pressing force signals are automatically and directly processed in an electronic measuring device to control the rotational speed of the loading wheel 7 and the height of the dispensing zone 6. To do this, after amplification of single signals in the amplifier 12, an average value is formed in the imaging unit 13, which can be compared with those set limit averages. In addition, in control unit 14, the maximum and minimum of all individual values can be compared with the set individual limit values, or the average value can be compared with the set limit average values, or st, the standard deviation with the set limits. The control unit 14, acting as a comparison device, is connected to both the driving motor 9 and the servomotor 10 to control the position of the metering guide 6 in height. Therefore, the speed of the loading wheel 7 and the position of the lower punches and thus the size of the cavities of the die can be established through it. The unit 14 controls the permutation of the metering devices only when it is known that the setting of the dosage should occur by adjusting with the help of the electric motor 9.
    Installation of the dosing zone b in height is also known as through the sensor 15 signals. In this sensor 15, the calculated average value of the pressing force is compared with a predetermined value. If the deviation lies outside the specified limits, then additional regulation is made through the sensor 15 signals.
    权利要求:
    Claims (1)
    [1]
    When the press operates, after reaching the predetermined rotational speed of the dies, through the control unit 14, the drive motor 9 of the loading wheel 7 is set in such a way that the deviations are minimal between the measured individual pressing forces. This is because the range of deviations in the pressing forces is detected in control unit 14. Thereafter, the first stage of the permutation is performed by applying a control pulse to the electric motor 9. Then, the range of deviations is again determined. If this range of deviations is greater, then two control pulses are applied to establish a minimum in the opposite direction. After which the comparison is again made. Control pulses are applied until the minimum is exceeded. After that, the direction of regulation is reversed again. In this case, the installation can be carried out in such a way that when the direction of regulation is changed, the amount of regulation is also automatically reduced. Comparing the achieved average pressing force with the specified pressing force sometimes leads to an undesirable deviation, so that by changing the position of the lower punch another free volume of the matrix arises, which leads to a different weight of the tablets. The rotation number must be adjusted again to this new position of the lower punch. loading wheel. Since after changing the position of the bottom punch between the power of the individual pressing forces, increased deviations may occur again. As a consequence, the regulation is carried out alternately and sequentially. Formula 1: A method for manufacturing tablets from powder materials, consisting in loading a metered amount of powder with a paddle feeder into the cavity of the matrix and subsequent pressing into the opposite: matrix and with the regulation of the number of loaded nopouwa by changing the number of revolutions of the blade feeder, which is different so that, in order to improve the quality of the tablets by providing them with a given density and mass, by controlling the amount of powder loaded by measurement, each pressing force determines the range of the pressing force and regulates the amount of the loaded powder until in comparison with the force of the previous one, it will not reach the minimum value, and when adjusting the volume of the cavity of the matrix, the reference value and regulate the volume of the cavity of the matrix until the pressing force from the reference value reaches the minimum value. 2 i. The method of claim 1, wherein the adjustment of the amount of the loaded powder and the volume of the cavity of the matrix is carried out sequentially. Sources of information taken into account in the examination 1. USSR author's certificate №613924, cl. at 30 V 11/12, 01.08.75.
    //
    15
    15
    类似技术:
    公开号 | 公开日 | 专利标题
    SU862816A3|1981-09-07|Method of making pellets from powdered materials
    US5322655A|1994-06-21|Method for monitoring and controlling the weights of each layer of a multilayer tablet
    US7981352B2|2011-07-19|Method and apparatus for quality surveillance during the manufacture of tablets
    US20050200038A1|2005-09-15|Method for controlling a rotary tablet press and such a press
    US3910737A|1975-10-07|Apparatus for automatically molding tablets including size and weight correction
    US4373888A|1983-02-15|Apparatus for mass-producing medical tablets
    JP5140071B2|2013-02-06|Method for controlling tablet molding machine and tablet molding machine
    JP3217122B2|2001-10-09|Compression molding machine
    US5838571A|1998-11-17|Tablet press monitoring and controlling method and apparatus
    US4680158A|1987-07-14|Circular pelletizing machine and method of controlling the same
    US4452579A|1984-06-05|Apparatus for producing tablets
    JP2975346B1|1999-11-10|Powder compression molding machine
    US4999151A|1991-03-12|Method of quality assurance in the manufacture of tablets
    GB1216397A|1970-12-23|Improvements in or relating to tablet forming machines
    US7032460B2|2006-04-25|Method for testing pressing tablets
    Armstrong et al.1987|Punch velocities during the compaction process
    US7797076B2|2010-09-14|Control unit for powder material compression molding machine
    JPH07112878B2|1995-12-06|Capsule filling machine
    JP2872286B2|1999-03-17|Method and apparatus for controlling weight of molded product in powder compression molding machine
    Jolliffe et al.1982|The design and use of an instrumented mG2 capsule filling machine simulator
    US4145174A|1979-03-20|Rotary tabletting machine
    SU537680A1|1976-12-05|Device for tabletting bulk materials
    JPH1099998A|1998-04-21|Tablet making machine
    Ridgway et al.1972|Automatic weight-control in a rotary tabletting machine
    JPH0780077B2|1995-08-30|Feedback Adjustment Method in Weight Control of Molded Parts of Rotary Tablet Machine
    同族专利:
    公开号 | 公开日
    JPS6339359B2|1988-08-04|
    GB2007582A|1979-05-23|
    IT7851176D0|1978-09-21|
    US4238431A|1980-12-09|
    DE2742572B1|1979-03-29|
    BE870676A|1979-01-15|
    IT1105961B|1985-11-11|
    AT365123B|1981-12-10|
    US4396564A|1983-08-02|
    GB2007582B|1982-03-10|
    FR2403792B1|1985-07-26|
    ATA679778A|1981-05-15|
    JPS54126720A|1979-10-02|
    CH632157A5|1982-09-30|
    FR2403792A1|1979-04-20|
    引用文献:
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    US3255716A|1962-12-10|1966-06-14|Upjohn Co|Measurement of forces within a tableting machine|
    GB1152061A|1966-06-14|1969-05-14|Upjohn Co|Pelleting Apparatus|
    DE1627927A1|1967-06-29|1971-02-18|Kilian & Co Gmbh|Tablet press|
    BE791465A|1971-11-16|1973-05-16|Upjohn Co|PRE-ARMING DEVICE FOR PASTILLER|
    US4000231A|1974-09-16|1976-12-28|Hydramet American Inc.|Method for compacting powders|
    DE2520662C3|1975-05-09|1983-11-03|Wilhelm Fette Gmbh, 2053 Schwarzenbek|Device for monitoring the pressing forces of the punches of a tablet press|
    GB1551954A|1975-05-28|1979-09-05|Hoffmann La Roche|Standardization of a physiochemical parameter of a batch of formulation in tabletted form|
    US4030868A|1976-03-15|1977-06-21|Hoffmann-La Roche Inc.|Force measurement and analysis particularly relating to rotary tablet presses|
    DE2742572B1|1977-09-22|1979-03-29|Fette Wilhelm Gmbh|Method of making tablets and tablet press|
    US4253811A|1979-07-13|1981-03-03|Firma Wilhelm Fette Gmbh|Method of and a device for sorting pellets upon their molding in a preforming press|DE2742572B1|1977-09-22|1979-03-29|Fette Wilhelm Gmbh|Method of making tablets and tablet press|
    JPS6219278B2|1979-07-13|1987-04-27|Takeda Chemical Industries Ltd|
    DE3131402A1|1981-08-07|1983-02-24|Kilian & Co GmbH, 5000 Köln|METHOD AND TABLET PRESS FOR THE SUCCESSFUL PRODUCTION OF A VARIETY OF TABLETS OF THE SAME WEIGHT|
    US4570229A|1983-09-19|1986-02-11|Pennwalt Corporation|Tablet press controller and method|
    EP0221091B1|1985-03-29|1990-03-07|Thomas Enginering, Inc.|Pharmaceutical tablet press control mechanism|
    US4943400A|1986-01-17|1990-07-24|Data Card Japan Ltd.|Method of manufacturing printing and embossing type elements|
    US4817006A|1986-03-28|1989-03-28|Thomas Engineering, Inc.|Pharmaceutical tablet press control mechanism|
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    JPH0444852U|1990-08-10|1992-04-16|
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    JP6505721B2|2014-01-10|2019-04-24|ジョンソン・アンド・ジョンソン・コンシューマー・インコーポレイテッド|Tablet manufacturing process using high frequency and lossy coated particles|
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    法律状态:
    优先权:
    申请号 | 申请日 | 专利标题
    DE2742572A|DE2742572B1|1977-09-22|1977-09-22|Method of making tablets and tablet press|
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